Runes - how to find runes | Collectibles Dishonored Guide
Last update: 11 May 2016
Some runes can be bought or received as a reward from NPCs, but overwhelming majority of them can be found during the gameplay. For finding the runes, it is best to use the Heart by selecting it from the inventory window, each time after a new area is loaded. An additional facilitation is the fact that each rune emits a characteristic sound which should help you find it.
It is worth noting that some runes have the Outsider chapel tied to them . As soon as you collect such a rune, a short cutscene of the meeting with the Outsider is initiated, so you do not have to perform any additional actions.
You collect runes in order to spend them afterwards to develop Corvo's powers (the above screenshot). An important piece of information is that you do not need to spend the runes to develop powers right after you obtain them. It is way better to save them up for later, especially that it is not possible to unlock all of the powers during a single example of a campaign.