Exploring Pratchett's apartment and the neighboring houses | Mission 4 - The Royal Physician Dishonored Guide
Last update: 11 May 2016
Right after you reach a new location, you will witness a conversation between Pratchett and one of the guards. It is worthwhile to wait until the end of the conversation, and seize the opportunity to explore Pratchett's apartment. The interesting thing is that, if you are fast enough, you will be able to steal Pratchett's key from Pratchett, before he manages to enter the building.
Do not worry if you do not manage to steal Pratchett's key. You can gain access to the building in a number of other ways. The easiest thing to do is teleport to one of the balconies (the above screenshot), but you can just as well enter from the side of the roof, or walk over a ledge.
On the building's ground floor, you can find gold and a rewire tool. On the first floor there is gold, food, a book, Piero's spiritual remedy and a cupboard that requires a key to open it. Inside the cupboard there is a 100-gold-piece worth sextant. If you haven't already eliminated Pratchett, this is where you should meet him. Since he is hostile towards Corvo, it would be a good idea to render him unconscious or put to sleep with a dart.
On the second floor of Pratchett's apartment, there is a safe (the above screenshot). The hint on how to open it was written down in the nearby Pratchett's Reminder. The puzzle consists in reading numbers that appear on the paintings hanging in the aristocrat's apartment - digit 4 on the painting with strolling people, 7 on the painting of a boat, and 3 on the painting featuring the slaughterhouse. Return to the safe and enter the combination: 473. Inside there are two bars and a rune. Wind up by exploring the remaining part of this floor, and find gold, a book and Sokolov's health elixir.
Apart from Pratchett's apartment, it would also be good to deal with the drawbridge and the remaining part of the district. I recommend that you take the main road and stop when you reach the window bars. Listen to the conversation between two criminals (the above screenshot) in order to learn that one of them (Alec) is currently being in the guards' custody. You will be able to free him later on. Make sure, however, that the two don't spot you, or else they will launch at you.
Around there are a few apartments on the upper floors, and it's easiest to access them by walking on rooftops (the best way to reach the rooftops is to take the staircase in Pratchett's apartment). The most valuable loot is to be found in the apartment patrolled by a deranged civilian (the above screenshot), whom it would be good to render unconscious or kill. Apart from gold, food and three log entries, there also is a rune.
I suggest that you wind up by exploring apartments located the closest to the drawbridge. Inside the apartment accessed via the stairs and the footbridge, there are gold and food. Inside the apartment right next to the enemy's outpost, (the above screenshot) there are gold, a note (Cards Scoreboard) and a rewire tool.