Choosing how to eliminate the Lord Regent | Mission 6 - Return to the Tower Dishonored Guide
Last update: 11 May 2016
Lord Regent may be disposed of by initiating a direct attack. I recommend against this, especially that Lord Regent won't give up without a fight if he spots you.
If you want to kill Lord Regent without alarm being raised, it is best to kill him as soon as he stops at the balcony (the above screenshot), or to shoot him from the side of the fireplace mentioned in the previous subsection. In both cases, it is recommended that you use your crossbow instead of the pistol that makes too much noise.
Definitely, the best solution is to remove Lord Regent from power without killing him. To do this, make sure that you have talked to the Propaganda Officer (the above screenshot; more about it, in the subsection entitled Explore Dunwall Tower's Third Floor. After you have seen the Propaganda Officer, enter [The Lord Regent's Chambers] and devote a few moments to their exploration. Note - If Lord Regent is any trouble, you can render him unconscious by choking him or putting him to sleep with a sleeping dart. This won't block the alternative solution.
In Lord Regent's Chambers, you can find Piero's spiritual remedy, two books, a note Lady Boyle Missing and a rune. The most important thing to do here is opening the safe with the combination obtained from the Officer, i.e. 935 . From the safe, collect gold, a letter Dead Drop and the Lord Regent's Confession Audiograph.
New Optional Quest: Play the Lord Regent's audiograph in the Broadcast Control Station
Equipped with the audiograph, return to the Tower's third floor (the staircase in the south-eastern corner), to reach once again the [Broadcast Control Station]. Interact with the Audiograph Player shown in the above screenshot, thanks to which you will discredit Lord Regent and complete the side quest. It is worth adding here that, if you want to witness Lord Regent's apprehension, you need to return to the second floor, to his chambers.
To wind up with, I will describe the circumstances in which you have alarmed Lord Regent to your presence in the Tower. If this happens, Lord Regent ill leave his chambers and go to the high-security area located on the Tower's roof, and more precisely to the [Regent's Safe Room]. In this case, exploration of the roof will turn out to be necessary. A detailed description of that location is contained in the next subsection of this guide, entitled Explore Dunwall Tower's Roof.