Defeat Harlow | Chapter 13 - With the Tide DI Riptide Guide
Last update: 11 May 2016
Immediately after finishing the cut scene, exit the room where you've talked with Harlow, as she'll start firing at you. During this encounter, you have two ways of behavior. The most obvious one is to use firearm (rifle or sniper rifle) and attack her from a distance.
Alternative option is to throw grenades and explosives to room with Harlow inside. Whatever you choose, remember to hide behind covers and picking up ammo and supplies regularly. First part of battle ends with a cut scene showing another speech of Harlow.
Second part will be even more difficult, because Harlow will use a mutagen. Notice also, that she picked up a chainsaw. So you have run around the laboratory, avoid direct contact and use good firearm. You can also throw mines here and there, but be careful not to explode.
Avoid also Harlow's molotovs. You can also unscrew valves, but it may be difficult as Harlow moves very quickly. Fight until another cut scene appears (when Harlow loses about 2/3 health).