Main quests - QUEST 5: A Meeting of the Minds - Ally: Desmond | Main quests F3: Point Lookout Guide
Last update: 11 May 2016
Received from: Desmond [Point Lookout]
Important: This section of the guide explains in detail what happens after you decide to side with Desmond (ghoul from the mansion) at the end of the fourth main quest. You can still change your allegiance - look for bold font in the text to find out where.
[#44]
Walkthrough: After you've witnessed the explosion take your time exploring what's left of the Calvert Mansion. Thankfully you won't be dealing with negative effects of radiation here, so you can remain in this area for as long as you want to. Your objective will be to find a small hatch leading to the Panic Room [#44]. Talk to Desmond and find out that he's located where the brain is hiding. You can now offer your help in getting rid of the brain, however you can also betray Desmond at any time by killing him without giving him a proper warning. If you do decide to betray him, make sure to follow the rest of the quest by reading a section of my guide titled QUEST 5: A Meeting of the Minds - Ally: The Brain (don't forget to take his card!). Once the conversation has ended follow Desmond by heading back outside.
[#45]
Keep following Desmond. You'll be heading towards Point Lookout Lighthouse, so it won't take too long for you to get there. The route itself should be safe. Once you're inside the lighthouse wait for a floor section to reveal a secret passageway [#45]. Obviously you must use the stairs here to gain access to an Underground Lab. Keep heading downwards and don't forget to explore a storage area along the way. This small room contains several useful items, including a Gatling laser, ammunition and medical supplies. Move on to the next section when you're done picking up new items.
[#46]
Remember that during your stay in the lab it would be wise to explore all rooms found along the way. Doing this will allow you to get your hands on some interesting treasures and most of these objects can be taken easily. Only some of the items will be hidden inside safes and lockers, but I assume that you've developed high Lockpicking skill by now. Eventually you'll get to a locked door [#46]. Use the switch to open it and get ready to destroy several security turrets at the same time. It shouldn't be a problem, even if you use less powerful weapons. Proceed to the lower floor and be ready to destroy a couple of robobrains on your way to the final area. Use EMP grenades/mines or energy weapons against them.
[#47]
Destroy the turrets when you get to a large oval area and take your time exploring your surroundings. Focus on finding an alpha security badge [#47]. You can use this card on a terminal to unlock a new passageway without having to hack into the system. Continue exploring lower levels of the compound and find the second badge (beta) to unlock a new door. It shouldn't be a big problem.
[#48]
Get rid of the last set of turrets before moving on any further and eventually you'll arrive in a large oval area with a cylinder. If you still want to cooperate with Desmond approach the cylinder and destroy it with a Gatling laser or something equally powerful [#48]. You can also talk to the brain and agree to betray Desmond at this point. Notice that he'll automatically become hostile, so you won't be allowed to surprise him anymore.
[#49]
Once you've destroyed the brain you should wait for Desmond to approach you and to initiate a new conversation. You won't receive too much gratitude, however you will be allowed to steal everything you see. Desmond will also give you a key to a nearby room. This storage space is located behind the cylinder [#49]. Explore it to find a large stash of weapons, ammunition and medical supplies. Microwave emitter is by far the best thing you can find here. Leave the lab using a small ladder or by going through the corridors again.