The Augs in Deus Ex: Human Revolution. Eight enemies we were sorry to kill
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One of the great advantages of the Deus Ex series has always been the plot, which leaves plenty of room for different shades of moral grey. In the 2011's Human Revolution, the moral quandaries revolve around the new divisions in a society torn between ordinary and technologically augmented people – still experiencing often overt discrimination. The latter group also includes the protagonist, Adam Jensen, so we naturally begin to identify to some extent with the augmented individuals. This in turn makes the very end of the game extremely unpleasant.
In the last act of Human Revolution, Hugh Darrow, one of the members of the Illuminati (yes, Deus Ex is a series loaded with conspiracy theories), activates a special biochip secretly installed in augmentations, which puts "enhanced" people into a state of murderous rage. Jensen, as the only technologically improved man still in his right mind, is left to travel to the Panchaea facility in the Arctic Ocean, from where the devastating signal is broadcasted.
The problem is that almost all of the station's staff are people with augmentations. So assuming that you have not made Jensen an absolute master of stealth, equipped with a series of augmentations that make it easier to stay unnoticed – sooner or later, a confrontation is bound to occur. And yet these people are not to blame here - they were simply used without their own knowledge by a representative of an all-powerful organization to show the world the potential dangers of transhumanism. Things are not made easier by the fact that as we approach the bloodthirsty brainwashed people, we hear their pitiful laments begging to end this nightmare. At least we are comforted by the fact that in the end, Jensen has a chance to turn off the signal and explain in his own broadcast who was behind the whole incident... only to find out at the beginning of the next part that there were so many legends around these traumatic events that our message made no difference.